Happy New Year to all who are following the progress of PD-MitoQUANT. We are pleased to provide you with our latest project update. Please find our January 2020 newsletter for download here.
Congratulations to all authors involved in the latest PD-MitoQUANT-acknowledged publication: Nolwen L. Rey, Luc Bousset, Sonia George, Zachary Madaj, Lindsay Meyerdirk, Emily Schulz, Jennifer A. Steiner, Ronald Melki and Patrik Brundin. PD-MitoQUANT PIs Luc Bousset and Ronald Melki are researchers at the Centre National de la Recherche Scientifique (CNRS). The open access paper entitled: α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb appears in Acta Neuropathologica Communications (2019) 7:221. The study was [...]
Olga Corti, PhD is a Research Director at the Institut du Cerveau et de la Moelle épinière (ICM) located in Paris, France. Olga is an expert in the functional analysis of protein products of Parkinson’s genes with a focus on mechanisms of mitochondrial quality control. We asked Olga some questions about her research and ICM’s role within PD-MitoQUANT. Within Parkinson’s research, which cell types and mechanisms are most interesting to you at the moment and why? Parkinson’s disease (PD) is [...]
PD-MitoQUANT PIs organise “pHysiopathology of Parkinson’s DisEase” (HOPE) 2020 conference at ICM, Paris
PD-MitoQUANT PIs Drs. Olga Corti, Stéphane Hunot (both based at the ICM) and Luc Bousset (Centre National de la Recherche Scientifique (CNRS)) are on the organizing committee of the 2nd "pHysiopathology of Parkinson's DisEase" (HOPE) conference taking place at the Institut du Cerveau et de la Moelle Epinière (ICM) in Paris from the 29th -31st January 2020. Following the success of the first edition and the positive feedback from participants regarding the latest scientific advances and the integration of basic [...]
At the sunny coastal town of Herzeliya, Israel, over 35 participants from 8 countries across Europe and Israel gathered for the 2nd plenary meeting of the PD-MitoQUANT IMI Consortium to discuss their latest progress toward investigating the role of mitochondrial dysfunction in Parkinson’s. Hosted by Teva Pharmaceutical Industries, researchers from academia, industry and non-profit organizations presented their progress on developing cellular and animal models of Parkinson’s to investigate the impact of alpha-synuclein fibrils on mitochondrial function. The emotional opening talks [...]
The annual Molecular and Computational Biology Symposium took place at the Conway Institute of Biomolecular and Biomedical Research in University College, Dublin (UCD) on the 21st and 22nd of November 2019. The symposium which involved international keynote speakers was organised by Ph.D. students from Systems Biology Ireland, the School of Veterinary Science, the School of Computer Science and the Conway Institute for Biomolecular and Biomedical research. Sandeep Chenna, RCSI At it, RCSI Research Assistant Sandeep Chenna presented PD-MitoQUANT- [...]
PD-MitoQUANT researcher Dr. Orla Watters from the Royal College of Surgeons in Ireland presented a poster entitled: The effects of local energetic stress on mitochondrial transport in primary cortical axons at the Society for Neuroscience (SfN) 2019 conference in Chicago, IL, USA. Other authors contributing to the study poster were N. M. C. Connolly, H-G. König, H. Düssmann, and J. H. M. Prehn. The poster was presented on Saturday, the 19th of October at 13:00-17:00 poster session. Download the pdf [...]
Researchers looking for a brief snapshot of PD-MitoQUANT to insert into their presentations need to look no further! With distinct audiences in mind, we have created two brief slide decks to describe the work undertaken in PD-MitoQUANT and to acknowledge all partners in and funders of the project. Download the slides for scientific presentations here. Download the slides for a general public audience here.
PD-MitoQUANT is one of twelve research projects launched by the Innovative Medicines Initiative, Europe's biggest public and private collaboration in life sciences, which aim to better understand and develop treatments for neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and multiple sclerosis. PD-MitoQUANT has joined forces with these research projects on the Neuronet platform to aid progress and expedite the delivery of novel treatments. A memorandum of understanding was jointly signed by Coordinator Prof Jochen Prehn, RCSI and Carlos Díaz, Coordinator of [...]
In October 2020, PD-MitoQUANT PI Dr Ronald Melki, CNRS is co-chairing the Jacques Monod conference which is themed: Protein phase transitions in ageing and age-related diseases: from atomic resolution to cellular solutions. Several PD-MitoQUANT PIs will present here. Where: Roscoff (Bretagne), France When: October 12-16, 2020 REGISTRATION REQUEST and ABSTRACT SUBMISSION DEADLINE: June 12, 2020 The conference- Cells and organisms maintain protein homeostasis in several cooperating ways, which include protein folding, degradation, and sequestration. During aging, the capacity to maintain protein [...]