In October 2020, PD-MitoQUANT PI Dr Ronald Melki, CNRS is co-chairing the Jacques Monod conference which is themed: Protein phase transitions in ageing and age-related diseases: from atomic resolution to cellular solutions. Several PD-MitoQUANT PIs will present here. Where: Roscoff (Bretagne), France When: October 12-16, 2020 REGISTRATION REQUEST and ABSTRACT SUBMISSION DEADLINE: June 12, 2020 The conference- Cells and organisms maintain protein homeostasis in several cooperating ways, which include protein folding, degradation, and sequestration. During aging, the capacity to maintain protein [...]
PD-MitoQUANT PI Dr Ronald Melki of the Centre National de la Recherche Scientifique, CNRS was an invited speaker at the International Symposium on Neurodegenerative Diseases organized by the University of Texas Southwestern O’Donnell Brain Institute in Dallas, Texas and the Texas Alzheimer’s Research and Care Consortium. The meeting took place on October 24 and 25, 2019 at the T. Boone Pickens Biomedical Building, NG3.11. Ronald's talk entitled "Prion-like propagation of alpha-synuclein and Tau assemblies in synucleinopathies and tauopathies" was [...]
Institut du Cerveau et de la Moelle Epinière (ICM) PI Dr Olga Corti presented her work and acknowledged PD-MitoQUANT at two recent conferences. The first conference presentation was on September 3, 2019, at the 23rd Biennial ESN meeting in Milan. Olga's talk was titled: “From dysfunction of PINK1/Parkin-mediated mitochondrial quality control to Parkinson’s disease”. See the entire programme here. In Coimbra, Olga presented at the 8th Workshop of the European Calcium Society. Her presentation was “Mechanisms underlying regulation of mitochondrial [...]
PD-MitoQUANT partners at Institut du Cerveau et de la Moelle Epinière recently co-authored a study entitled "The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells." in Scientific Reports on August 14, 2019. This work was undertaken by M. Jacoupy, E. Hamon-Keromen, A.Ordureau, Z. Erpapazoglou, F. Coge, J.-C. Corvol, O. Nosjean, C. Mannoury laCour, M. J. Millan, J.A. Boutin, J.W. Harper, A. Brice, D.Guedin, C.A.Gautier and O. Corti. Congratulations to the team! "Most of over a [...]
On September 3, 2019, PD-MitoQUANT PI Dr Ronald Melki, Team Leader of the Protein misfolding and aggregation in neurodegenerative diseases group at CNRS delivered the keynote lecture at the 4-day SYNUCLEIN meeting. Following on from the keynote talk, Ronald chaired a round table discussion titled: Alpha-synuclein aggregation: how does it happen? Participants at the table included Daniel Otzen, Ronald Melki and Hilal Lashuel. The 2019 meeting which took place in Ofir on the outskirts of Porto in Portugal was themed [...]
A review was recently published in the Journal of Neurochemistry which acknowledged PD-MitoQUANT research funding. "α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities" authored by a team consisting of Parvez Alam, Luc Bousset, Ronald Melki and Daniel E. Otzen appeared in the 29 June 2019 issue. Ronald and Luc are PD-MitoQUANT PIs from the Centre National de la Recherche Scientifique, the CNRS in France. Download the open access paper here. Congratulations to all!
A few questions were posed to PI Prof Dr Donato (Dino) DiMonte to gain his views on his work in Parkinson research and PD-MitoQUANT, in general. Dino is a senior researcher and leads the Neurodegeneration and Neuroprotection in Parkinson’s Disease Group at the German Center for Neurodegenerative Diseases (DZNE). Please describe your day to day work. It is difficult to describe a “typical” day of work. Most of the time, our working schedule involves specific tasks that vary from day [...]
The 5th World Parkinson Congress (WPC) was held in Kyoto, Japan from June 4– 7, 2019. More than 3,000 people from more than 60 countries attended the meeting. At this meeting, Dr Ronald Melki of the Centre National de la Recherche Scientifique (CNRS) and PD-MitoQUANT PI presented: "What is alpha-synuclein- The biology". Through Ronald's talk, PD-MitoQUANT funding was acknowledged. Dr Ronald Melki, CNRS at WPC 2019 The WPC 2019 hosted an international, interdisciplinary forum showcasing the most important [...]
Beckie Port "From innovation to better treatments" is the title of a blog post published on 27 May 2019 by Dr Beckie Port. Beckie is Research Communications Manager at PD-MitoQUANT partner Parkinson's UK. This blog entry announces partnerships with two pan-European, IMI-funded research projects: PD-MitoQUANT and Neuronet. In it, Beckie describes how these collaborative projects aim to accelerate research and deliver new treatments for Parkinson’s. Read the full blog post here.