Our partner Parkinson's UK is hosting an online research conference on September 24th and 25th, 2020. The 2020 theme is "Accelerating research and improving care". This is a CPD-accredited entirely online meeting held over two days. Keynote lectures will be delivered live from around the world. Symposia will be available on-demand and downloadable for 30 days after the event, and, crucially, poster presentations and networking will take place throughout. The Parkinson's UK Online Research Conference is kindly supported by Guarantors [...]
The RCSI, Royal College of Surgeons in Ireland team comprised of Orla Watters, Niamh M. C. Connolly, Hans-Georg König, Heiko Duessmann and Jochen Prehn published a PD-MitoQUANT-acknowledged paper in the Journal of Neuroscience. The study entitled: AMPK preferentially depresses retrograde transport of axonal mitochondria during localised nutrient deprivation appeared online on May 11th 2020. DOI: https://doi.org/10.1523/jneurosci.2067-19.2020 Congratulations to the entire team! This is the seventh on the growing list of PD-MitoQUANT-acknowledged publications. Also, visit our new Research Gate profile here.
Congratulations to Maya Bendifallah, Virginie Redeker, Elodie Monsellier, Luc Bousset*, Tracy Bellande, and Ronald Melki* for the publication of their recent study entitled: Interaction of the chaperones alpha B-crystallin and CHIP with fibrillar alpha-synuclein: Effects on internalization by cells and identification of interacting interfaces. The paper appeared in the journal Biochemical and Biophysical Research Communications on May 17, 2020. This is the sixth PD-MitoQUANT-referenced paper. Find the entire list, read the abstracts and download the pdfs of these open-access studies [...]
With headquarters in Denmark, Lundbeck is a global pharmaceutical company highly committed to improving the quality of life of people living with brain diseases. For this purpose, Lundbeck is engaged in research, drug discovery development, manufacturing, marketing and sale of pharmaceuticals across the world. The company’s products are targeted at disease areas within psychiatry and neurology. Within PD-MitoQUANT, Lundbeck: is scientific co-leader as part of the PD-MitoQUANT Executive Team, evaluates a range of α-synuclein (α-αSyn) fibril species to select the most [...]
The public, including patients, can and should be involved in all aspects of research, including study design, communication, and ethics. Patients bring unique knowledge and skills to projects, which can improve the quality of research. The Innovative Medicines Initiative encourages public and patient involvement (PPI) in all of its projects. PD-MitoQUANT is fortunate to have two people with Parkinson’s involved in the project through our patient advocacy partner Parkinson’s UK. Here, we meet Paula Scurfield. Paula was diagnosed with Parkinson’s [...]
PD-MitoQUANT is fortunate to have two people with Parkinson’s, Richard Campbell and Paula Scurfield, involved in the project through our patient advocacy partner Parkinson’s UK (www.parkinsons.org.uk). Recently, Richard wrote a blog entitled “Getting involved in an international research project on Parkinson’s”. "Paula Scurfield and I are part of the Parkinson’s UK Research Support Network and have joined the project as patient and public representatives. Our role is to advise on how information about the project is communicated, and how findings are shared [...]
Congratulations to our partners at the Centre National de la Recherche Scientifique (CNRS) for their March 17, 2020, open-access paper published in Scientific Reports. The paper entitled "The expression level of alpha-synuclein in different neuronal populations is the primary determinant of its prion-like seeding" was authored by Josquin Courte, Luc Bousset, Ysander Von Boxberg, Catherine Villard, Ronald Melki & Jean-Michel Peyrin. Find the entire list of PD-MitoQUANT acknowledged papers here: https://www.pdmitoquant.eu/publications/
The open-access study titled: Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs published by the team consisting of AN Shrivastava, Luc Bousset, M Renner, V Redeker, J Savistchenko, A Triller and Ronald Melki was recently published in the Biophysical Journal on the 27th of January 2020. Congratulations to the whole team! See the growing list of PD-MitoQUANT-acknowledged publications here: https://www.pdmitoquant.eu/publications
Happy New Year to all who are following the progress of PD-MitoQUANT. We are pleased to provide you with our latest project update. Please find our January 2020 newsletter for download here.
Congratulations to all authors involved in the latest PD-MitoQUANT-acknowledged publication: Nolwen L. Rey, Luc Bousset, Sonia George, Zachary Madaj, Lindsay Meyerdirk, Emily Schulz, Jennifer A. Steiner, Ronald Melki and Patrik Brundin. PD-MitoQUANT PIs Luc Bousset and Ronald Melki are researchers at the Centre National de la Recherche Scientifique (CNRS). The open access paper entitled: α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb appears in Acta Neuropathologica Communications (2019) 7:221. The study was [...]