Our partner Parkinson's UK is hosting an online research conference on September 24th and 25th, 2020. The 2020 theme is "Accelerating research and improving care". This is a CPD-accredited entirely online meeting held over two days. Keynote lectures will be delivered live from around the world. Symposia will be available on-demand and downloadable for 30 days after the event, and, crucially, poster presentations and networking will take place throughout. The Parkinson's UK Online Research Conference is kindly supported by Guarantors of Brain and is held every 2 years. It brings together professionals from research and healthcare to share ideas, develop collaborations and accelerate progress towards new treatments for Parkinson's. For more information, a list of keynote speakers, a preliminary programme, ticket prices and to register, please click here. In addition, abstract submissions for poster and platform presentation can be made through an online system upon purchasing a ticket - a link [...]
The RCSI, Royal College of Surgeons in Ireland team comprised of Orla Watters, Niamh M. C. Connolly, Hans-Georg König, Heiko Duessmann and Jochen Prehn published a PD-MitoQUANT-acknowledged paper in the Journal of Neuroscience. The study entitled: AMPK preferentially depresses retrograde transport of axonal mitochondria during localised nutrient deprivation appeared online on May 11th 2020. DOI: https://doi.org/10.1523/jneurosci.2067-19.2020 Congratulations to the entire team! This is the seventh on the growing list of PD-MitoQUANT-acknowledged publications. Also, visit our new Research Gate profile here.
Congratulations to Maya Bendifallah, Virginie Redeker, Elodie Monsellier, Luc Bousset*, Tracy Bellande, and Ronald Melki* for the publication of their recent study entitled: Interaction of the chaperones alpha B-crystallin and CHIP with fibrillar alpha-synuclein: Effects on internalization by cells and identification of interacting interfaces. The paper appeared in the journal Biochemical and Biophysical Research Communications on May 17, 2020. This is the sixth PD-MitoQUANT-referenced paper. Find the entire list, read the abstracts and download the pdfs of these open-access studies here. *PD-MitoQUANT PIs
The current situation regarding the Coronavirus disease (COVID-19) is significantly impacting the research community, including the PD-MitoQUANT international consortium. We anticipate that the precise nature of these impacts will evolve over the coming weeks and months. Our institutions' priority is the safety and wellbeing of all people, including our own research teams. The consortium is working together to come up with solutions to reduce delays to the project as a result of the practical measures taken to contain the virus.
With headquarters in Denmark, Lundbeck is a global pharmaceutical company highly committed to improving the quality of life of people living with brain diseases. For this purpose, Lundbeck is engaged in research, drug discovery development, manufacturing, marketing and sale of pharmaceuticals across the world. The company’s products are targeted at disease areas within psychiatry and neurology. Within PD-MitoQUANT, Lundbeck: is scientific co-leader as part of the PD-MitoQUANT Executive Team, evaluates a range of α-synuclein (α-αSyn) fibril species to select the most promising for further investigation by the project, transfers their established α-Syn fibril primary neuron seeding assay to other partners, investigates mitophagy, transfers samples of α-Syn fibril seeded primary neurons to PD-MitoQUANT partner Radboud University Nijmegen Medical Centre for investigations of correlations between morphology and functionality, establishes the kinetics of the pathology development in a striatal stereotaxic α-Syn fibril injection mouse model to define the best timepoint for assessment of mitochondrial [...]